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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REV3L
All Species:
9.09
Human Site:
S466
Identified Species:
25
UniProt:
O60673
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60673
NP_002903.3
3130
352776
S466
E
K
E
E
M
E
L
S
L
V
M
S
Q
R
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086055
3130
352672
S466
E
K
E
E
M
E
L
S
L
V
M
S
Q
R
W
Dog
Lupus familis
XP_539084
3058
344677
D422
R
S
S
T
E
E
D
D
S
S
S
E
E
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q61493
3122
350641
L465
I
E
K
E
E
M
E
L
S
V
V
M
S
Q
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520025
1544
171107
Chicken
Gallus gallus
XP_426179
3135
353106
S455
E
K
E
E
M
E
L
S
L
I
M
S
Q
R
W
Frog
Xenopus laevis
NP_001163919
3139
352589
E462
E
P
Q
V
E
K
E
E
M
E
L
S
I
L
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786092
3425
381348
L498
W
I
I
L
D
E
E
L
E
K
E
E
E
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14284
1504
172939
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.4
90
N.A.
86.5
N.A.
N.A.
35.1
72.3
58.1
N.A.
N.A.
N.A.
N.A.
N.A.
31.5
Protein Similarity:
100
N.A.
97.9
92.9
N.A.
91.8
N.A.
N.A.
41.4
82.8
72.4
N.A.
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
N.A.
100
6.6
N.A.
13.3
N.A.
N.A.
0
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
13.3
N.A.
40
N.A.
N.A.
0
100
40
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
12
12
0
0
0
0
0
0
0
% D
% Glu:
45
12
34
45
34
56
34
12
12
12
12
23
23
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
12
0
0
0
0
0
0
12
0
0
12
0
0
% I
% Lys:
0
34
12
0
0
12
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
12
0
0
34
23
34
0
12
0
0
12
0
% L
% Met:
0
0
0
0
34
12
0
0
12
0
34
12
0
0
23
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
34
23
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
0
0
0
0
34
12
% R
% Ser:
0
12
12
0
0
0
0
34
23
12
12
45
12
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
34
12
0
0
0
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _